BDBM472879 Ethyl 4-((4-(((2-(5-bromothiophen-2- yl))cyclopropyl)amino)methyl)- 4-fluoropiperidin-1-yl)methyl) benzoate::US10836743, Compound A104

SMILES CCOC(=O)c1ccc(CN2CCC(F)(CNC3CC3c3ccc(Br)s3)CC2)cc1

InChI Key InChIKey=HYBJCXWOQALNFD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472879   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472879(Ethyl 4-((4-(((2-(5-bromothiophen-2- yl))cycloprop...)
Affinity DataIC50:  140nMAssay Description:Screening method: lysine-specific demethylase 1 (LSD1) activity screeningInstrument: microplate reader Envision™ (PerkinElmer, USA).MATERIALS: Human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent