BDBM472906 Piperidin-4-ylmethyl 4-fluoro-4-((((1R,2S)-2-phenyl- cyclopropyl)amino)methyl) piperidine-1-carboxylate::US10836743, Compound (1R,2S)-A43

SMILES FC1(CN[C@@H]2C[C@H]2c2ccccc2)CCN(CC1)C(=O)OCC1CCNCC1

InChI Key InChIKey=CMYNDDNZDLGSJZ-VQTJNVASSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 472906   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472906(Piperidin-4-ylmethyl 4-fluoro-4-((((1R,2S)-2-pheny...)
Affinity DataIC50:  49.7nMAssay Description:Screening method: lysine-specific demethylase 1 (LSD1) activity screeningInstrument: microplate reader Envision™ (PerkinElmer, USA).MATERIALS: Human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472906(Piperidin-4-ylmethyl 4-fluoro-4-((((1R,2S)-2-pheny...)
Affinity DataIC50: >1.00E+5nMAssay Description:Screening method: Monoamine oxidase MAOA and MAOB activity screeningInstrument: microplate reader Envision™ (PerkinElmer, USA).MATERIALS: Human recom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM472906(Piperidin-4-ylmethyl 4-fluoro-4-((((1R,2S)-2-pheny...)
Affinity DataIC50:  2.97E+4nMAssay Description:Screening method: Monoamine oxidase MAOA and MAOB activity screeningInstrument: microplate reader Envision™ (PerkinElmer, USA).MATERIALS: Human recom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent