BDBM47305 BDBM156659::US9023354, AD4-10483

SMILES Cc1cccc(NC(c2ccc(cc2)C(F)(F)F)c2ccc3cccnc3c2O)n1

InChI Key InChIKey=HUHLXTYKRKEJDP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 47305   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47305(BDBM156659 | US9023354, AD4-10483)
Affinity DataIC50:  4.00E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47305(BDBM156659 | US9023354, AD4-10483)
Affinity DataIC50:  4.60E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent