BDBM47307 BDBM50339143::US9023354, AD4-10942

SMILES Oc1c(ccc2cccnc12)C(Nc1cccnc1)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=DENCCOZMOOLBIS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 47307   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47307(BDBM50339143 | US9023354, AD4-10942)
Affinity DataIC50:  1.80E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBotulinum neurotoxin type A(Clostridium botulinum)
U.S. Army Medical Research Institute Of Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM47307(BDBM50339143 | US9023354, AD4-10942)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of protease activity of recombinant Clostridium botulinum BoNT/A (1 to 425) light chain after 5 mins by HPLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
U.S. Army Medical Research Institute Of Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM47307(BDBM50339143 | US9023354, AD4-10942)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of protease activity of recombinant full-length Clostridium botulinum BoNT/A light chain after 5 mins by HPLC-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed