BDBM47310 US9023354, AD4-13243

SMILES Cc1cc(Cl)cnc1NC(c1ccc2cccnc2c1O)c1c(F)c(F)c(OCC(F)(F)F)c(F)c1F

InChI Key InChIKey=DJRVQLYQYXYHOA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 47310   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM47310(US9023354, AD4-13243)
Affinity DataIC50:  8.50E+3nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent