BDBM473118 N-{5-methanesulfonyl- 4H,5H,6H,7H- pyrazolo[1,5-a]pyrazin- 2-yl}-6-{1H- pyrrolo[3,2-b]pyridin-6- yl}imidazo[1,2- a]pyridin-8-amine::US10842803, Structure TABLE 1.48

SMILES CS(=O)(=O)N1CCn2nc(Nc3cc(cn4ccnc34)-c3cnc4cc[nH]c4c3)cc2C1

InChI Key InChIKey=XGIBBFYEAXESGG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 473118   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kronos Bio

US Patent
LigandPNGBDBM473118(N-{5-methanesulfonyl- 4H,5H,6H,7H- pyrazolo[1,5-a]...)
Affinity DataIC50:  3.70E+3nMAssay Description:A master mix minus Syk enzyme is prepared containing 1X Cell Signaling kinase buffer (25 mM Tris-HCl, pH 7.5, 5 mM beta-glycerophosphate, 2 mM dithio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent