BDBM473794 N-hydroxy-2-((2-methoxy-5-(trifluoromethyl)benzyl)amino)pyrimidine-5-carboxamide::US10858323, Compound 3

SMILES COc1ccc(cc1CNc1ncc(cn1)C(=O)NO)C(F)(F)F

InChI Key InChIKey=YJGLQGXOWLMXEQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 473794   

TargetHistone deacetylase 1(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM473794(N-hydroxy-2-((2-methoxy-5-(trifluoromethyl)benzyl)...)
Affinity DataIC50:  68nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM473794(N-hydroxy-2-((2-methoxy-5-(trifluoromethyl)benzyl)...)
Affinity DataIC50:  2nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM473794(N-hydroxy-2-((2-methoxy-5-(trifluoromethyl)benzyl)...)
Affinity DataIC50:  105nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM473794(N-hydroxy-2-((2-methoxy-5-(trifluoromethyl)benzyl)...)
Affinity DataIC50:  82nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent