BDBM474107 Pazopanib metabolite M27::US10858364, Compound M27
SMILES Cc1n(C)nc2cc(Nc3ccnc(Nc4ccc(C)c(c4)S(N)(=O)=O)n3)ccc12
InChI Key InChIKey=XWOGXAVHJKKNPO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 474107
Affinity DataKi: 188nMAssay Description:Inhibitory activity on BTK wild type (BTK-WT) and BTK Cys481Ser mutant (BTK-C481S) was measured using the LanthaScreen assay technology from ThermoFi...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Ramos B cells (ATCC, cat no. CRL-1923) were plated in 24-wells culture plates at 2×106 cells per well in a total volume of 900 μL DMEMF12+10% FB...More data for this Ligand-Target Pair