BDBM474172 7-(4-methoxybenzyl)-6-methyl-3- (2-methyltetrahydrofuran-3- yl)imidazo[1,5-a]pyrazin-8(7H)- one, stereoisomer 1::US10858362, Example 55, isomer 1::US10912773, Example 55-isomer-1::US11472810, Example 55, isomer 1

SMILES COc1ccc(Cn2c(C)cn3c(ncc3c2=O)[C@@H]2CCO[C@@H]2C)cc1

InChI Key InChIKey=PZHZVFDPQAUVKV-RHSMWYFYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 474172   

LigandPNGBDBM474172(7-(4-methoxybenzyl)-6-methyl-3- (2-methyltetrahydr...)
Affinity DataIC50:  20nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474172(7-(4-methoxybenzyl)-6-methyl-3- (2-methyltetrahydr...)
Affinity DataIC50:  10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474172(7-(4-methoxybenzyl)-6-methyl-3- (2-methyltetrahydr...)
Affinity DataIC50:  17nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474172(7-(4-methoxybenzyl)-6-methyl-3- (2-methyltetrahydr...)
Affinity DataIC50:  20nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474172(7-(4-methoxybenzyl)-6-methyl-3- (2-methyltetrahydr...)
Affinity DataIC50:  10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474172(7-(4-methoxybenzyl)-6-methyl-3- (2-methyltetrahydr...)
Affinity DataIC50:  17nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474172(7-(4-methoxybenzyl)-6-methyl-3- (2-methyltetrahydr...)
Affinity DataIC50:  20nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474172(7-(4-methoxybenzyl)-6-methyl-3- (2-methyltetrahydr...)
Affinity DataIC50:  10nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474172(7-(4-methoxybenzyl)-6-methyl-3- (2-methyltetrahydr...)
Affinity DataIC50:  17nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474172(7-(4-methoxybenzyl)-6-methyl-3- (2-methyltetrahydr...)
Affinity DataIC50:  20nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474172(7-(4-methoxybenzyl)-6-methyl-3- (2-methyltetrahydr...)
Affinity DataIC50:  10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474172(7-(4-methoxybenzyl)-6-methyl-3- (2-methyltetrahydr...)
Affinity DataIC50:  17nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent