BDBM474210 7-(4-methoxybenzyl)-6-methyl-3- (1-(4-methylthiazol-2- yl)ethyl)imidazo[1,5-a]pyrazin- 8(7H)-one::US10858362, Example 90::US10912773, Example 90::US11472810, Example 90

SMILES COc1ccc(Cn2c(C)cn3c(ncc3c2=O)C(C)c2nc(C)cs2)cc1

InChI Key InChIKey=XRYJHUBBBIIQDO-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 474210   

LigandPNGBDBM474210(7-(4-methoxybenzyl)-6-methyl-3- (1-(4-methylthiazo...)
Affinity DataIC50:  34nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474210(7-(4-methoxybenzyl)-6-methyl-3- (1-(4-methylthiazo...)
Affinity DataIC50:  15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474210(7-(4-methoxybenzyl)-6-methyl-3- (1-(4-methylthiazo...)
Affinity DataIC50:  23nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474210(7-(4-methoxybenzyl)-6-methyl-3- (1-(4-methylthiazo...)
Affinity DataIC50:  34nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474210(7-(4-methoxybenzyl)-6-methyl-3- (1-(4-methylthiazo...)
Affinity DataIC50:  15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474210(7-(4-methoxybenzyl)-6-methyl-3- (1-(4-methylthiazo...)
Affinity DataIC50:  23nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474210(7-(4-methoxybenzyl)-6-methyl-3- (1-(4-methylthiazo...)
Affinity DataIC50:  34nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474210(7-(4-methoxybenzyl)-6-methyl-3- (1-(4-methylthiazo...)
Affinity DataIC50:  15nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474210(7-(4-methoxybenzyl)-6-methyl-3- (1-(4-methylthiazo...)
Affinity DataIC50:  23nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474210(7-(4-methoxybenzyl)-6-methyl-3- (1-(4-methylthiazo...)
Affinity DataIC50:  34nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474210(7-(4-methoxybenzyl)-6-methyl-3- (1-(4-methylthiazo...)
Affinity DataIC50:  15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474210(7-(4-methoxybenzyl)-6-methyl-3- (1-(4-methylthiazo...)
Affinity DataIC50:  23nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent