BDBM474212 6-(cyclopentylmethyl)-7-(4- methoxybenzyl)-3-(tetrahydro- 2H-pyran-4-yl)imidazo[1,5- a]pyrazin-8(7H)-one::US10858362, Example 92::US10912773, Example 92::US11472810, Example 92

SMILES COc1ccc(Cn2c(CC3CCCC3)cn3c(ncc3c2=O)C2CCOCC2)cc1

InChI Key InChIKey=TUNXEGCQHJFZRL-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 474212   

LigandPNGBDBM474212(6-(cyclopentylmethyl)-7-(4- methoxybenzyl)-3-(tetr...)
Affinity DataIC50:  71nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474212(6-(cyclopentylmethyl)-7-(4- methoxybenzyl)-3-(tetr...)
Affinity DataIC50:  11nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474212(6-(cyclopentylmethyl)-7-(4- methoxybenzyl)-3-(tetr...)
Affinity DataIC50:  79nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474212(6-(cyclopentylmethyl)-7-(4- methoxybenzyl)-3-(tetr...)
Affinity DataIC50:  71nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474212(6-(cyclopentylmethyl)-7-(4- methoxybenzyl)-3-(tetr...)
Affinity DataIC50:  11nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474212(6-(cyclopentylmethyl)-7-(4- methoxybenzyl)-3-(tetr...)
Affinity DataIC50:  79nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474212(6-(cyclopentylmethyl)-7-(4- methoxybenzyl)-3-(tetr...)
Affinity DataIC50:  71nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474212(6-(cyclopentylmethyl)-7-(4- methoxybenzyl)-3-(tetr...)
Affinity DataIC50:  11nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474212(6-(cyclopentylmethyl)-7-(4- methoxybenzyl)-3-(tetr...)
Affinity DataIC50:  79nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474212(6-(cyclopentylmethyl)-7-(4- methoxybenzyl)-3-(tetr...)
Affinity DataIC50:  71nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474212(6-(cyclopentylmethyl)-7-(4- methoxybenzyl)-3-(tetr...)
Affinity DataIC50:  11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM474212(6-(cyclopentylmethyl)-7-(4- methoxybenzyl)-3-(tetr...)
Affinity DataIC50:  79nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent