BDBM474234 5-(5-amino-2-((3-fluoropyridin-2-yl)methyl)-7- (4-methoxyphenyl)-[1,2,4]triazolo[1,5-c]pyrimidin- 8-yl)-1-methylpyridin-2(1H)-one::US10858365, Compound 61::US11629147, Cmpd. 61
SMILES COc1ccc(cc1)-c1nc(N)n2nc(Cc3ncccc3F)nc2c1-c1ccc(=O)n(C)c1
InChI Key InChIKey=PHWLGGRFNGIWGN-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 474234
Affinity DataIC50: 4.20nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Affinity DataIC50: 122nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair