BDBM474348 (S)-6-benzhydryl-11-hydroxy-2,3-dimethyl- 5H-imidazo[1,2-a]pyrido[2,1-c]pyrazin- 10(6H)-one::US10858366, Example 14::US11453677, Example 14

SMILES Cc1nc2-c3c(O)c(=O)ccn3[C@H](Cn2c1C)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=CYVDNIFUERLGCM-HXUWFJFHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474348   

TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474348((S)-6-benzhydryl-11-hydroxy-2,3-dimethyl- 5H-imida...)
Affinity DataIC50:  100nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474348((S)-6-benzhydryl-11-hydroxy-2,3-dimethyl- 5H-imida...)
Affinity DataIC50:  100nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent