BDBM474349 (S)-6-((R)-(4-fluorophenyl)(phenyl)methyl)- 11-hydroxy-5H- imidazo[2',1':3,4]pyrazino[1,2-b]pyridazin- 10(6H)-one::US10858366, Example 17::US11453677, Example 17

SMILES Oc1c2-c3nccn3C[C@H]([C@H](c3ccccc3)c3ccc(F)cc3)n2ncc1=O

InChI Key InChIKey=OARZVVYLDAKONC-IEBWSBKVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474349   

TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474349((S)-6-((R)-(4-fluorophenyl)(phenyl)methyl)- 11-hyd...)
Affinity DataIC50:  20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474349((S)-6-((R)-(4-fluorophenyl)(phenyl)methyl)- 11-hyd...)
Affinity DataIC50:  20nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent