BDBM474356 (S)-6-((S)-(4-fluorophenyl)(m-tolyl)methyl)- 11-hydroxy-5,6-dihydro-10H- imidazo[2',1':3,4]pyrazino[1,2-b]pyridazin-10- one::US10858366, Example 38::US11453677, Example 38

SMILES Cc1cccc(c1)[C@@H]([C@H]1Cn2ccnc2-c2c(O)c(=O)cnn12)c1ccc(F)cc1

InChI Key InChIKey=CMLWGUOZJRQYDC-QUCCMNQESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474356   

TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474356((S)-6-((S)-(4-fluorophenyl)(m-tolyl)methyl)- 11-hy...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474356((S)-6-((S)-(4-fluorophenyl)(m-tolyl)methyl)- 11-hy...)
Affinity DataIC50:  40nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent