BDBM474360 3-((R)-(3-fluorophenyl)((S)-11-hydroxy-10- oxo-5,6-dihydro-10H- imidazo[2',1':3,4]pyrazino[1,2-b]pyridazin-6- yl)methyl)benzonitrile::US10858366, Example 46::US11453677, Example 46

SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3cccc(F)c3)c3cccc(c3)C#N)n2ncc1=O

InChI Key InChIKey=NAHBNEWIHQCPGN-UYAOXDASSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474360   

TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474360(3-((R)-(3-fluorophenyl)((S)-11-hydroxy-10- oxo-5,6...)
Affinity DataIC50:  50nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474360(3-((R)-(3-fluorophenyl)((S)-11-hydroxy-10- oxo-5,6...)
Affinity DataIC50:  50nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent