BDBM474378 (S)-6-benzhydryl-11-hydroxy-N-(2- methoxyethyl)-10-oxo-5,6-dihydro-10H- imidazo[1,2-a]pyrido[2,1-c]pyrazine-3- carboxamide::US10858366, Example 71

SMILES COCCNC(=O)c1cnc2-c3c(O)c(=O)ccn3[C@H](Cn12)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=WGXVUACURPSUHB-OAQYLSRUSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 474378   

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474378((S)-6-benzhydryl-11-hydroxy-N-(2- methoxyethyl)-10...)
Affinity DataEC50:  1.90E+4nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase()
Novartis

US Patent
LigandPNGBDBM474378((S)-6-benzhydryl-11-hydroxy-N-(2- methoxyethyl)-10...)
Affinity DataEC50:  2.70E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474378((S)-6-benzhydryl-11-hydroxy-N-(2- methoxyethyl)-10...)
Affinity DataEC50: >5.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent