BDBM474380 5-benzhydryl-10-hydroxy-3-methyl-4,5- dihydroimidazo[4,5-d]pyrido[1,2-b]pyridazin- 9(3H)-one::US10858366, Example 82

SMILES Cn1cnc-2c1CN(C(c1ccccc1)c1ccccc1)n1ccc(=O)c(O)c-21

InChI Key InChIKey=HZRVWUGIRZTKCH-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 474380   

TargetNeuraminidase(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
Novartis

US Patent
LigandPNGBDBM474380(5-benzhydryl-10-hydroxy-3-methyl-4,5- dihydroimida...)
Affinity DataEC50:  1.00E+3nMAssay Description:For influenza NA assays, MDCK cells were plated in Phenol Red-free DMEM (Gibco) supplemented with 2 mM L-Glutamine, 1% sodium pyruvate (Cellgro, Mana...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase()
Novartis

US Patent
LigandPNGBDBM474380(5-benzhydryl-10-hydroxy-3-methyl-4,5- dihydroimida...)
Affinity DataEC50:  1.40E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Novartis

US Patent
LigandPNGBDBM474380(5-benzhydryl-10-hydroxy-3-methyl-4,5- dihydroimida...)
Affinity DataEC50:  4.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent