BDBM474459 US10881668, Compound 503

SMILES Cc1nnc2[C@@H](CC(=O)NCC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1

InChI Key InChIKey=QXWJFGXUZLPVCL-GOSISDBHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474459   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM474459(US10881668, Compound 503)
Affinity DataIC50:  44nMAssay Description:ssays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM474459(US10881668, Compound 503)
Affinity DataIC50:  89nMAssay Description:ssays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent