BDBM474461 US10881668, Compound 505

SMILES Cc1sc-2c(c1C)C(=N[C@H](CC(=O)NCCC(F)F)c1nnc(C)n-21)c1ccc(Cl)cc1

InChI Key InChIKey=NHMJYXDPZTZGQX-MRXNPFEDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474461   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM474461(US10881668, Compound 505)
Affinity DataIC50:  29nMAssay Description:ssays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM474461(US10881668, Compound 505)
Affinity DataIC50:  75nMAssay Description:ssays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent