BDBM474493 N-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(cyclopropylmethoxy)benzyl)threonine::US10882833, Example 8

SMILES C[C@@H](O)[C@H](NCc1cc(Cl)c(OCc2cccc(c2Br)-c2ccccc2)cc1OCC1CC1)C(O)=O

InChI Key InChIKey=FJADAHLJUXELSD-CRYYWNKWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474493   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM474493(N-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(cyclo...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PDL1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM474493(N-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(cyclo...)
Affinity DataIC50:  10.2nMAssay Description:1. In vitro activity evaluation: Cisbio PD-1/PD-L1 binding assay kit was applied for the detection method of in vitro enzymology level.Screening Prin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent