BDBM474494 2-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(cyclopropylmethoxy)benzyl amino)-3-hydroxypropanamide::US10882833, Example 9

SMILES NC(=O)[C@H](CO)NCc1cc(Cl)c(OCc2cccc(c2Br)-c2ccccc2)cc1OCC1CC1

InChI Key InChIKey=ZRQXKMYNDQWELD-QHCPKHFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474494   

TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM474494(2-(4-(2-bromo-3-phenylbenzyloxy)-5-chloro-2-(cyclo...)
Affinity DataIC50:  81.6nMAssay Description:1. In vitro activity evaluation: Cisbio PD-1/PD-L1 binding assay kit was applied for the detection method of in vitro enzymology level.Screening Prin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent