BDBM474502 (S,S)—N-(4-(2-bromo-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzyloxy)-5-chloro-2-(cyclopropylmethoxy)benzyl)-4-hydroxyproline::US10882833, Example 17

SMILES O[C@H]1C[C@H](N(Cc2cc(Cl)c(OCc3cccc(c3Br)-c3ccc4OCCOc4c3)cc2OCC2CC2)C1)C(O)=O

InChI Key InChIKey=JLLTUBDWNGWHPK-DHLKQENFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474502   

TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Institute of Materia Medica, Chinese Academy of Medical Sciences

US Patent
LigandPNGBDBM474502((S,S)—N-(4-(2-bromo-3-(2,3-dihydrobenzo[b][1,4]dio...)
Affinity DataIC50:  40.5nMAssay Description:1. In vitro activity evaluation: Cisbio PD-1/PD-L1 binding assay kit was applied for the detection method of in vitro enzymology level.Screening Prin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent