BDBM474571 (E)-1-[(3aS,3bR,6aS,6bR)-5-(1H- benzotriazole-5-carbonyl)-octahydro- cyclobuta[1,2-c;3,4-c']dipyrrol-2-yl]-3-(4- trifluoromethoxy-phenyl)-propenone::US10849881, Example 1.003

SMILES FC(F)(F)Oc1ccc(\C=C\C(=O)N2C[C@H]3[C@@H](C2)[C@@H]2CN(C[C@H]32)C(=O)c2ccc3[nH]nnc3c2)cc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 474571   

TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM474571((E)-1-[(3aS,3bR,6aS,6bR)-5-(1H- benzotriazole-5-ca...)
Affinity DataIC50:  8.5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent