BDBM475494 1-[6-(Propane-1-sulfonyl)-5-trifluoromethoxy-1H-::US10851083, Example 106::US11618744, Example 106

SMILES CCCS(=O)(=O)c1cc2[nH]c(nc2cc1OC(F)(F)F)-n1cc(cn1)C(O)=O

InChI Key InChIKey=ZLGJXFDVZKMFRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475494   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475494(1-[6-(Propane-1-sulfonyl)-5-trifluoromethoxy-1H- |...)
Affinity DataIC50:  31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475494(1-[6-(Propane-1-sulfonyl)-5-trifluoromethoxy-1H- |...)
Affinity DataIC50:  31.6nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent