BDBM475744 US10849881, Example 1.019::[(3aR,3bS,6aR,6bS)-5-((R)-4,5,6,7- tetrahydro-1H-benzotriazole-5-carbonyl)- octahydro-cyclobuta[1,2-c;3,4-c']dipyrrol- 2-yl]-(5-trifluoromethoxy-1H-indol-2-yl)- methanone

SMILES FC(F)(F)Oc1ccc2[nH]c(cc2c1)C(=O)N1C[C@H]2[C@@H]3CN(C[C@@H]3[C@H]2C1)C(=O)[C@@H]1CCc2[nH]nnc2C1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475744   

TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM475744(US10849881, Example 1.019 | [(3aR,3bS,6aR,6bS)-5-(...)
Affinity DataIC50:  11.5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent