BDBM475786 (4-isopropoxy-naphthalen-2-yl)- [(3aR,3bS,6aR,6bS)-5-((R)-4,5,6,7- tetrahydro-1H-benzotriazole-5-carbonyl)- octahydro-cyclobuta[1,2-c;3,4-c']dipyrrol- 2-yl]-methanone::US10849881, Example 1.059

SMILES CC(C)Oc1cc(cc2ccccc12)C(=O)N1C[C@H]2[C@@H]3CN(C[C@@H]3[C@H]2C1)C(=O)[C@@H]1CCc2[nH]nnc2C1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475786   

TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM475786((4-isopropoxy-naphthalen-2-yl)- [(3aR,3bS,6aR,6bS)...)
Affinity DataIC50:  1.30nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent