BDBM475840 (3aR,3bS,6aR,6bS)-5-(1H-Benzotriazole-5-carbonyl)-octahydro-cyclobuta[1,2-c;3,4-c′]dipyrrole-2-carboxylic Acid 3,5-dichloro-benzyl Ester::US10849881, Example 2.001

SMILES Clc1cc(Cl)cc(COC(=O)N2C[C@H]3[C@@H](C2)[C@@H]2CN(C[C@H]32)C(=O)c2ccc3[nH]nnc3c2)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475840   

TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM475840((3aR,3bS,6aR,6bS)-5-(1H-Benzotriazole-5-carbonyl)-...)
Affinity DataIC50:  4.5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent