BDBM476198 US10865384, Compound IM-25::US10865384, Example 3a
SMILES CS(=O)c1ccc(cc1)-c1nc(c([nH]1)C1=CCOCC1)-c1ccc(F)cc1
InChI Key
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 476198
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 454nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 1.49E+3nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 5.89E+3nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 1.49E+3nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 5.89E+3nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair