BDBM476199 US10865384, Compound IM-23::US10865384, Example 3b
SMILES Fc1ccc(cc1)-c1nc([nH]c1C1=CCOCC1)-c1c(F)cccc1F
InChI Key InChIKey=UQDJIVYNWZDXAM-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 476199
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 55nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 548nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 751nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 548nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research
US Patent
Agency For Science, Technology and Research
US Patent
Affinity DataIC50: 751nMAssay Description:Table 2: The p38 MAPK IC50 values of selected compounds except IM-32 to IM-44 were determined using the HitHunter™ p38 MAP kinase binding assay from ...More data for this Ligand-Target Pair