BDBM476219 US10865384, Compound D4476::US11633415, Compound D-4476::US11759530, Compound Table1.3

SMILES NC(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccccn1)-c1ccc2OCCOc2c1

InChI Key InChIKey=DPDZHVCKYBCJHW-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 476219   

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  157nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  88nMAssay Description:Table 3: Small molecules were tested for their inhibitory activities towards casein kinase 1 delta (CK1δ) and 1 epsilon (CK1ϵ). The in vit...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
The Broad Institute

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  321nMAssay Description:In order to identify inhibitors of CSNK1A1, the CSNK1A1 knockdown signatures in CMap were compared to all CMap compound signatures, and resultant com...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  500nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  1.20E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Agency For Science, Technology and Research

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  3.00E+5nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  4.30E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  10nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  2.40E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  4.30E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  320nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  10nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  2.40E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I homolog hhp1(Fission yeast)
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  200nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent