BDBM476451 2-chloro-3,4-dimethylphenyl (3S)-3- {[4-(aminomethyl)-3- methoxybenzyl]carbamoyl}-4-{(2R)- 2-[(2-benzyl-2-azaspiro[4.5]dec-8- yl)amino]butanoyl}piperazine-1- carboxylate::US10875851, Example 107

SMILES CC[C@@H](NC1CCC2(CCN(Cc3ccccc3)C2)CC1)C(=O)N1CCN(C[C@H]1C(=O)NCc1ccc(CN)c(OC)c1)C(=O)Oc1ccc(C)c(C)c1Cl

InChI Key InChIKey=ILRYUBRXPHPWHS-LABSLUORSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476451   

TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476451(2-chloro-3,4-dimethylphenyl (3S)-3- {[4-(aminometh...)
Affinity DataIC50:  14nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent