BDBM477045 US10882853, Compound 5

SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCC1CC(C1)N1CCOCC1

InChI Key InChIKey=MPVXOIXRPUPSAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477045   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Lanova Medicines

US Patent
LigandPNGBDBM477045(US10882853, Compound 5)
Affinity DataIC50:  39.9nMAssay Description:1. Methods(1) 4 μL of prepared kinase buffer solution or 4 μL of kinase solution (100% inhibition control) were added into a 384-hole plate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Lanova Medicines

US Patent
LigandPNGBDBM477045(US10882853, Compound 5)
Affinity DataIC50:  20.6nMAssay Description:1. Methods(1) 4 μL of prepared kinase buffer solution or 4 μL of kinase solution (100% inhibition control) were added into a 384-hole plate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent