BDBM477064 US10882857, Example 4.02::US11673888, Example 4.02::[3-(2,2-Dimethylpropanoylamino)-5-(trifluoromethyl)pyridin-2-yl]methyl 2-(4-sulfamoylpiperidine-1-carbonyl)-4,6-dihydrothieno[2,3-c]pyrrole-5-carboxylate and 2,2-dimethyl-N-[2-[[2-(4-sulfamoylpiperidine-1-carbonyl)-4,6-dihydrothieno[2,3-c]pyrrol-5-yl]methyl]-5-(trifluoromethyl)pyridin-3-yl]propanamide

SMILES CC(C)(C)C(=O)Nc1cc(cnc1COC(=O)N1Cc2cc(sc2C1)C(=O)N1CCC(CC1)S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=PUHPITNNQBUMLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477064   

TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM477064(US10882857, Example 4.02 | US11673888, Example 4.0...)
Affinity DataIC50:  1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM477064(US10882857, Example 4.02 | US11673888, Example 4.0...)
Affinity DataIC50:  1nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent