BDBM477706 US10889568, Compound 81::[(R)-4-(6-Amino-pyridin-3-yl)-2- hydroxymethyl-piperazin-1-yl]-(4- methoxy-5-phenoxy-pyridin-2-yl)- methanone

SMILES COc1cc(ncc1Oc1ccccc1)C(=O)N1CCN(C[C@@H]1CO)c1ccc(N)nc1

InChI Key InChIKey=QZZVOELQJNALHL-QGZVFWFLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477706   

TargetShort transient receptor potential channel 6(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM477706(US10889568, Compound 81 | [(R)-4-(6-Amino-pyridin-...)
Affinity DataIC50:  71nMAssay Description:The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC6 construct and screened by conventional calcium imaging t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent