BDBM477954 6-(3-hydroxyazetidin-1-yl)-2-oxo-4-(7-azaspiro[3.5]nonane-7-yl)-1,2-dihydro-1,7-naphthyridin-3-carbonitrile ::US10889591, Compound 51::US11434248, Compound 51
SMILES OC1CN(C1)c1cc2c(N3CCC4(CCC4)CC3)c(C#N)c(=O)[nH]c2cn1
InChI Key InChIKey=KMHDGBBPVHERFL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 477954
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences
US Patent
Nanjing Transthera Biosciences
US Patent
Affinity DataIC50: 5nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences
US Patent
Nanjing Transthera Biosciences
US Patent
Affinity DataIC50: 5nMAssay Description:1. Experimental materials and instrumentsPDE9A2 Enzyme (BPS, Cat. No. 60090)384-well plate (Perkin Elmer, Cat. No. 6007279)2. Experimental procedureP...More data for this Ligand-Target Pair