BDBM477963 6-methoxy-2-oxo-4-(6-azaspiro[2.5]octane-6-yl)-1,2-dihydro-1,7-naphthyridin-3-carbonitrile ::US10889591, Compound 64::US11434248, Compound 64
SMILES COc1cc2c(N3CCC4(CC4)CC3)c(C#N)c(=O)[nH]c2cn1
InChI Key InChIKey=DSRUCJAYTORBBQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 477963
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences
US Patent
Nanjing Transthera Biosciences
US Patent
Affinity DataIC50: 14nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences
US Patent
Nanjing Transthera Biosciences
US Patent
Affinity DataIC50: 14nMAssay Description:1. Experimental materials and instrumentsPDE9A2 Enzyme (BPS, Cat. No. 60090)384-well plate (Perkin Elmer, Cat. No. 6007279)2. Experimental procedureP...More data for this Ligand-Target Pair