BDBM477990 6-(cyclopropyl(hydroxy)methyl)-4-(4-methoxy-4-methylpiperidin-1-yl)-2-oxo-1,2-dihydro-1,7-naphthyridin-3-carbonitrile ::US10889591, Compound 130::US11434248, Compound 130
SMILES COC1(C)CCN(CC1)c1c(C#N)c(=O)[nH]c2cnc(cc12)C(O)C1CC1
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 477990
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences
US Patent
Nanjing Transthera Biosciences
US Patent
Affinity DataIC50: 3nMAssay Description:Test substance: Compounds of the invention, prepared by the corresponding examples of the invention1. Experimental materials and instrumentsPDE9A2 En...More data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Nanjing Transthera Biosciences
US Patent
Nanjing Transthera Biosciences
US Patent
Affinity DataIC50: 3nMAssay Description:1. Experimental materials and instrumentsPDE9A2 Enzyme (BPS, Cat. No. 60090)384-well plate (Perkin Elmer, Cat. No. 6007279)2. Experimental procedureP...More data for this Ligand-Target Pair