BDBM478932 2-(4-(4-acryloylpiperazin-1-yl)phenyl)-N-(5-cyclopropyl-1H-pyrazol-3- yl)propanamide (Isomer-2 of compound-17)::US10894786, Comp. No 19

SMILES C[C@@H](C(=O)Nc1cc([nH]n1)C1CC1)c1ccc(cc1)N1CCN(CC1)C(=O)C=C

InChI Key

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 478932   

TargetCyclin-dependent kinase 13(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478932(2-(4-(4-acryloylpiperazin-1-yl)phenyl)-N-(5-cyclop...)
Affinity DataIC50:  5.81E+3nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 12(Homo sapiens)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478932(2-(4-(4-acryloylpiperazin-1-yl)phenyl)-N-(5-cyclop...)
Affinity DataKd: >100nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent