BDBM478966 (R)-N-(2-chloro-4-(3-((5- chloropyrimidin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US10894788, Example 6::US10894788, Example 72::US11390618, Example 72
SMILES Clc1cnc(N[C@@H]2CCN(C2)C(=O)c2ccc(NC(=O)C=C)c(Cl)c2)nc1
InChI Key InChIKey=ZWHVUOHIYOGOMY-CYBMUJFWSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 478966
Affinity DataIC50: <100nMAssay Description:For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...More data for this Ligand-Target Pair