BDBM478984 (R)-N-(4-(3-((5-chloro-4-(2,2,2- trifluoroethoxy)pyrimidin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US10894788, Example 24::US11390618, Example 24
SMILES FC(F)(F)COc1nc(N[C@@H]2CCN(C2)C(=O)c2ccc(NC(=O)C=C)cc2)ncc1Cl
InChI Key InChIKey=LZNVCSUQLJKANE-CQSZACIVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 478984
Affinity DataIC50: <100nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...More data for this Ligand-Target Pair