BDBM479350 (3-((S)-5-amino-13-oxa-9- azadispiro[3.1.56.24]tridecan- 9-yl)-6-(((6aS,8S)-8-((methoxymethoxy)methyl)- 6a,7,8,9-tetrahydro-6H-pyrido[3,2-b]pyrrolo[1,2- d][1,4]oxazin-4-yl)thio)pyrazin-2-yl)methanol::US10894797, Compound 39::US11034705, Compound 39::US11518772, Compound 39
SMILES COCOC[C@H]1C[C@H]2COc3c(Sc4cnc(N5CCC6(COC7(CCC7)[C@H]6N)CC5)c(CO)n4)ccnc3N2C1
InChI Key InChIKey=OPEZBSGNVCPIIK-OSOCVKALSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 479350
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Nikang Therapeutics
US Patent
Nikang Therapeutics
US Patent
Affinity DataIC50: 7nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Nikang Therapeutics
US Patent
Nikang Therapeutics
US Patent
Affinity DataIC50: 7nMAssay Description:The phosphatase reactions were carried out at room temperature in 384-well black polystyrene plates (Greiner Bio-One, Cat #784076) using assay buffer...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:The phosphatase reactions were carried out at room temperature in 384-well black polystyrene plates (Greiner Bio-One, Cat #784076) using assay buffer...More data for this Ligand-Target Pair