BDBM480842 7-(4-methoxybenzyl)-6-methyl-3- yl)imidazo[1,5-a]pyrazin-8(7H)- one, stereoisomer 3::US10905688, Example 55, isomer 3::US11472810, Example 55, isomer 3

SMILES COc1ccc(Cn2c(C)cn3c(ncc3c2=O)[C@H]2CCO[C@@H]2C)cc1

InChI Key InChIKey=PZHZVFDPQAUVKV-PBHICJAKSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 480842   

LigandPNGBDBM480842(7-(4-methoxybenzyl)-6-methyl-3- yl)imidazo[1,5-a]p...)
Affinity DataIC50:  13nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM480842(7-(4-methoxybenzyl)-6-methyl-3- yl)imidazo[1,5-a]p...)
Affinity DataIC50:  3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM480842(7-(4-methoxybenzyl)-6-methyl-3- yl)imidazo[1,5-a]p...)
Affinity DataIC50:  8nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM480842(7-(4-methoxybenzyl)-6-methyl-3- yl)imidazo[1,5-a]p...)
Affinity DataIC50:  13nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM480842(7-(4-methoxybenzyl)-6-methyl-3- yl)imidazo[1,5-a]p...)
Affinity DataIC50:  8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM480842(7-(4-methoxybenzyl)-6-methyl-3- yl)imidazo[1,5-a]p...)
Affinity DataIC50:  8nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM480842(7-(4-methoxybenzyl)-6-methyl-3- yl)imidazo[1,5-a]p...)
Affinity DataIC50:  13nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM480842(7-(4-methoxybenzyl)-6-methyl-3- yl)imidazo[1,5-a]p...)
Affinity DataIC50:  3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM480842(7-(4-methoxybenzyl)-6-methyl-3- yl)imidazo[1,5-a]p...)
Affinity DataIC50:  3nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays were performed in 60 μL samples containing a fixed amount of the PDE1 enzyme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent