BDBM481153 US10906900, Reference 22f

SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(F)nc2[nH]1

InChI Key InChIKey=XXRXTSVWBPYSMG-UHFFFAOYSA-N

Data  2 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 481153   

TargetAlpha-synuclein(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481153(US10906900, Reference 22f)
Affinity DataKi:  14.8nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481153(US10906900, Reference 22f)
Affinity DataKi:  349nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-synuclein(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481153(US10906900, Reference 22f)
Affinity DataKd:  0.790nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM481153(US10906900, Reference 22f)
Affinity DataKd:  16.8nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent