BDBM481153 US10906900, Reference 22f
SMILES CN(C)c1ccc(cc1)C#Cc1cc2ccc(F)nc2[nH]1
InChI Key InChIKey=XXRXTSVWBPYSMG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 481153
Affinity DataKi: 14.8nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataKi: 349nMAssay Description:Table 5: Fresh solutions of the test compounds (2.5 mM in DMSO) are diluted in PBS pH7.4, at concentrations between 0.5 nM and 5 μM in the prese...More data for this Ligand-Target Pair
Affinity DataKd: 0.790nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein [1-42](Homo sapiens (Human))
Centre National De La Recherche Scientifique
US Patent
Centre National De La Recherche Scientifique
US Patent
Affinity DataKd: 16.8nMAssay Description:Table 6 & 7: Fresh solutions of each test compound (2.5 mM in DMSO) are diluted in PBS pH=7.4 at concentrations between 0.5 nM and 5 μM in the p...More data for this Ligand-Target Pair