BDBM481790 1-[(4-[2-[4- (difluoromethoxy)phenyl]ethyl]- 5-oxo-4,5-dihydro-1,3,4- oxadiazol-2-yl)methyl]-6- methyl-7-oxo-1H,6H,7H- pyrazolo[4,3- d]pyrimidine-3-carbonitrile::US10913742, Example 32

SMILES Cn1cnc2c(nn(Cc3nn(CCc4ccc(OC(F)F)cc4)c(=O)o3)c2c1=O)C#N

InChI Key InChIKey=ZNZNLOPOYMLSDO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481790   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481790(1-[(4-[2-[4- (difluoromethoxy)phenyl]ethyl]- 5-oxo...)
Affinity DataIC50:  36nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent