BDBM481808 3-[3-(4- chlorophenyl)cyclobutyl]-5- [(7-methyl-6-oxo-purin-1- yl)methyl]-1,3,4-oxadiazol- 2-one::US10913742, Example 50

SMILES Cn1cnc2ncn(Cc3nn([C@H]4C[C@@H](C4)c4ccc(Cl)cc4)c(=O)o3)c(=O)c12

InChI Key InChIKey=CYWFSLKYTRCPPA-MQMHXKEQSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 481808   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481808(3-[3-(4- chlorophenyl)cyclobutyl]-5- [(7-methyl-6-...)
Affinity DataIC50:  14nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM481808(3-[3-(4- chlorophenyl)cyclobutyl]-5- [(7-methyl-6-...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at rat TRPA1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481808(3-[3-(4- chlorophenyl)cyclobutyl]-5- [(7-methyl-6-...)
Affinity DataIC50:  7.40nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO cells measured by calcium based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed