BDBM481814 3-((4-(4-chlorophenethyl)-5- oxo-4,5-dihydro-1,3,4- oxadiazol-2-yl)methyl)-5- methyl-4-oxo-4,5-dihydro-3H- pyrrolo[3,2-d]pyrimidine-7- carbonitrile::US10913742, Example 56

SMILES Cn1cc(C#N)c2ncn(Cc3nn(CCc4ccc(Cl)cc4)c(=O)o3)c(=O)c12

InChI Key InChIKey=RFXWMKXVVDBBLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481814   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481814(3-((4-(4-chlorophenethyl)-5- oxo-4,5-dihydro-1,3,4...)
Affinity DataIC50:  168nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent