BDBM481822 US10913742, Example 65::trans-2-[[4-[3-(4- chlorophenyl)cyclobutyl]-5- oxo-1,3,4-oxadiazol-2- yl]methyl]pyrido[1,2- a]pyrazine-1,6-dione
SMILES Clc1ccc(cc1)[C@H]1C[C@@H](C1)n1nc(Cn2ccn3c(cccc3=O)c2=O)oc1=O
InChI Key InChIKey=LNHYIPIWVZDRTE-KOMQPUFPSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 481822
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 21.1nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair