BDBM481843 5-methyl-3-[[5-oxo-4-[rac- (2R)-2-(4-chlorophenyl)-2- fluoro-ethyl]-1,3,4-oxadiazol- 2-yl]methyl]pyrido[3,2- d]pyrimidine-4,6-dione::US10913742, Example 87

SMILES Cn1c2c(ccc1=O)ncn(Cc1nn(C[C@H](F)c3ccc(Cl)cc3)c(=O)o1)c2=O

InChI Key InChIKey=LFYAILSQQZVGPM-ZDUSSCGKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481843   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481843(5-methyl-3-[[5-oxo-4-[rac- (2R)-2-(4-chlorophenyl)...)
Affinity DataIC50:  43.8nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent