BDBM481848 5-[(7-methyl-6-oxo-purin-1- yl)methyl]-3-[(1R,3R)-3-(4- fluorophenyl)cyclopentyl]- 1,3,4-oxadiazol-2-one::US10913742, Example 92

SMILES Cn1cnc2ncn(Cc3nn([C@@H]4CC[C@H](C4)c4ccc(F)cc4)c(=O)o3)c(=O)c12

InChI Key InChIKey=WRJCSDBKLNHRAA-UKRRQHHQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481848   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481848(5-[(7-methyl-6-oxo-purin-1- yl)methyl]-3-[(1R,3R)-...)
Affinity DataIC50:  8.26nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent